Category Archives: Bioinformatics

Modeling Evolution in vitro and in silico

Artificial life is no new idea. Computer scientists have investigated and made use of many of the principals around AI for years. However, in silico models of evolution have been shown to produce some form of self-replicating, mutating, artificial life. How far have these models gone, and where will they go next? Is this playing God?

Identity by State SNP Analysis: Find Relatives, Test Paternity, and Determine Allele Sharing

Identity by State SNP Analysis can be used to find relatives, test paternity, examine inbreeding, and look at recombinations between siblings.

Use Family SNP Data to Phase Your Own Genome

With family trio SNP data (father, mother, child), it is possible to determine the haplotypes for the child. A step-by-step guide along with a program to execute this task is presented.

Ideograms: The Art of Drawing Chromosomes

Ideograms are graphical representations of the genome. Along with appeasing the need to visualize the less lively genotype data that is obtained from microarrays, ideograms can actually help in the analysis of data. Methods for creating ideograms along with sample ideograms are discussed.

Phasing: Determining Which SNPs are Inherited Together

Biallelic DNA microarray data SNPs, can be made much more useful if it haplotype information is also available. However, the process of phasing biallelic data is not so simple.

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